My research is focused on examination of the NF-κB pathway in the response to DNA damage as a prerequisite to understanding the role of this pathway in the formation and treatment of cancer. Moreover, given the central role of NF-κB to aging, my studies also involve examination of NF-κB and DNA damage in aging and chronic disease. In general, my scientific studies have revolved around the p50/NFkb1 subunit and its role in regulating signaling associated with replication stress and ATR.

In addition, my work also involves examination of the treatment of the brain cancer, glioblastoma, and mechanisms to improve response to therapy in these tumors. These studies include not only basic science work in cells, but also translation studies in animals and clinical trials in humans and pet dogs.

I have a very broad scientific background that encompasses basic biochemistry and molecular biology, as well as animal studies and rigorous clinical training. I was promoted to associate professor in 2012 and subsequently to professor in 2016. I am also now the Director of Neurosurgical Oncology in the section of Neurosurgery.

Over that past 15 years, I have mentored many students and trainees from all levels including high school, undergrads, graduate students and post-doctoral fellows. I have had two medical students who were awarded Howard Hughes Medical Research fellowships and one student who was awarded an NIH F32 grant.