A Ludwig Lausanne study found that recurrent tumors of the brain cancer glioblastoma multiforme grow out of fibrous scars left by the treatment of the initial tumor. The scars create a niche that shields residual glioma cells from immune clearance and pushes them into a dormant state in which they resist therapy.
Read MoreA Ludwig MIT study uncovered a subpopulation of T cells in the white pulp of the spleen whose descendants contribute enormously to anti-tumor responses following checkpoint blockade therapy. These cells are in a state of differentiation known as intermediate exhaustion and specifically require for activation only low levels of cancer antigens in the spleen.
Three Ludwig Center trainees took a few minutes out of their very busy schedules to tell us about their lives, scientific fascinations, avocational passions and views on a variety of issues.
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